Other skin disorders caused by low levels of B12
A study in the National Library of Health looked at hyperpigmentation and other skin disorders indicating low B12 levels.
Hyperpigmentation with generalised weakness may be the initial presentation of several systemic conditions with a vitamin B12 deficiency being present very rarely as hyperpigmentation, said the study.
It added: “The cutaneous manifestation of Vitamin B12 deficiency is skin hyperpigmentation, vitiligo, hair changes, and recurrent angular stomatitis.
“Hyperpigmentation of the extremities, especially over the dorsum of the hands and feet, with accentuation over the interphalangeal joints and terminal phalanges associated with pigmentation of the oral mucosa is characteristic of vitamin B12 deficiency.”