In a study published in the National Library of Health, toxicity due to multiple doses of vitamin B12 in a case report was investigated.
In the study the clinical consequences of excess vitamin B12 supplementation in a young woman was analysed.
The women were treated with multiple daily doses of 1mg of cyanocobalamin for severe pernicious anaemia.
After a total dose of 12mg, the women developed acne, facial ruddiness and insomnia.
“Although these symptoms of cobalamin toxicity were unexpected and unusual, the case reminds us that the administration of any drug is not entirely safe,” said the study.
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